10.00am Ugo Piomelli FRSC
Department of Mechanical and Materials Engineering – Queen’s University
Turbulence simulations: unravelling disorder, one vortex at a time
Turbulence is everywhere: it affects aircraft drag and fuel consumption, blood flow, weather patterns. Yet no theory has been developed that can explain it, and numerical models have become one of the most useful tools to study it. These models yield the life story of each fluid particle, each whorl, vortex or eddy; hunting for answers in such datasets is as challenging as generating the data itself. Examples of such hunting expeditions will be presented, to show how simulations can improve the understanding of turbulence, and how this understanding can be applied to the real life problems that motivate this work.
11.00am Una Roman D’Elia – College of New Scholars, Artists and Scientists
Department of Art History and Art Conservation – Queen’s University,
Donatello and Pygmalion
According to the ancient tale, Pygmalion’s dearest wish was granted when his sculpture came to life, her flesh warm and yielding. This story and countless other myths, jokes, and miracles of statues coming to life were recounted in the Renaissance with a mixture of desire, awe, and fear. Donatello created life-size naturalistic sculptures in full color that seem to enact Pygmalion’s dream, but he also found ways to make his sculptures conspicuously artful and to frustrate attempts to treat them as living idols.
2.00pm Elizabeth Eisenhauer FRSC
Department of Oncology – Queen’s University
Moving from the lab to the clinic – 30 years of progress in cancer treatment
The last 30 years have seen major changes in the basic biological understanding of cancer etiology and progression which have, in turn, led to novel approaches to prevent, screen, and treat cancer. The impact of these collective advances has been to reduce the mortality rates from cancer in Canada in males from 335 to 235 per 100,000 population and in females from 207 to 171 per 100,000 population between 1987 and 2016. While some of these successes can be attributed to prevention efforts (e.g. smoking cessation) or screening programs (e.g. breast and cervix cancers), improvements in cancer treatments have also played an important role.
Laboratory research has revealed cancers to be associated with numerous acquired genetic abnormalities. In the past 2 decades new drugs designed to target many of these genetic changes have been evaluated in clinical trials and many have had a positive impact on cancer survival. In Canada, the Canadian Cancer Trials Group (CCTG) at Queen’s (formerly the NCIC Clinical Trials Group) has been an international leader in the study of many of these new drugs and my research as well as that of other investigators in that group have contributed to these gains. Current clinical research efforts are focused on the translation from the laboratory on the mechanisms through which malignant tissues avoid immune surveillance into approaches and therapies that “uncloak” tumours and render them sensitive to auto-immune attack. New drugs capable of this feat have proven effective in melanoma, lung cancer and others – and once again Canadian research has and is continuing to play a pivotal role in these achievements. The presentation will review specific examples of novel treatments coming from the lab and the role the research I and others at CCTG have played in studying them in cancer patients and, based on that work, bringing them into clinical practice.
3.00pm Donald Beecher FRSC
Department of English - Carleton University
Boccaccio's "Tale of Titus and Gisippius" (Decameron X.8) with a Coda on Friendship from a Cognitive Perspective
Renaissance writers were intrigued by the humanist notions of friendship originating in antiquity and in their stories sought to demonstrate how such commitments might come to pass. Nowhere is that more clearly demonstrated than in Boccaccio's fine tale from the Decameron about the perfect amity between Titus and Gisippus. Yet rationales for the mental calculations intrinsic to such friendships remain challenging even for recent cognitive philosophers. Why would a self-interested brain want to venture into such potentially costly arrangements? And the truth of that matter is that we still do not know.
12.00 pm Principal’s Luncheon
4.00pm Conversation (cash bar) at the University Club
The seminar and lunch for Fellows and guests are supported financially by contributions from the Royal Society of Canada, the Principal of Queen’s University, donations from Fellows, and a charge of $30 per person for attendees (with the exception of speakers and invited guests) by payment at the door on April 22nd. Guests are welcome. The talks are free and are open to the public.
We look forward to welcoming you to this year’s RSC Seminar, Pierre du Prey FRSC (Queen’s Art) and Michael Sayer FRSC (Queen’s Physics), Co-Chairs
Please RSVP as soon as convenient and for the lunch by April 19th, 2017: email@example.com, or 613 531-4853.